RNA Modifications: More Insights, More Impact

Go Beyond RNA-Seq

Turnkey profiling and in-lab kits for m6A, inosine, and pseudouridine—one platform, one workflow.

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RNA Modifications: More Insights, More Impact

Go Beyond RNA-Seq

Turnkey profiling and in-lab kits for m6A, inosine, and pseudouridine—one platform, one workflow.

Request a Quote Products & Pricing

Why Researchers Choose EpiPlex

Multi-target detection—m6A, inosine, and pseudouridine in a single workflow
Built for real samples—FFPE, liquid biopsy, and RNA-limited inputs
Spike-in normalization for confident, interpretable quantification
Same platform for services and in-lab kits—send samples or run it yourself

One Platform for Epitranscriptomics

EpiPlex™ Kits & Services

Proximity barcoding and engineered binders for multi-modification detection. Turnkey services (Uni-Mod, Duo-Mod, Tri-Mod) or in-lab RNA Mod Encoding and UDI kits.

Services Products

EpiScout™ Analysis

Machine-learning–powered software turns raw sequencing data into actionable insights. Run on DNAnexus with a Compute Token or through our service pipeline.

EpiScout™ Compute Token

I am very excited by the ability to simultaneously map multiple epitranscriptomic modifications in a single assay and we have been impressed by the high quality and reproducibility of the data generated from the samples we have tested.

Gregory Lab Harvard

I am super excited about this collaboration. I've been interested in RNA modifications almost since I joined [this company]. It was one of the things that just seemed to make sense, but it's very, very nascent. So when you guys appeared on the scene, I was extremely excited, because some of our collaborations with academic partners have not been nearly so smooth and successful.

Vice President $2B+ Diagnostics Company

The data look fantastic and is exactly what I have observed with m6A-seq

Brockdorff Lab University of Oxford

The AlidaBio EpiPlex kit proved to have several advantages over alternative methods. We observed ease-of-use going from input RNA to sequence-ready libraries all in one kit, time savings and usability for situations with limited amounts of RNA, and lower background than other methods. The inclusion of bioinformatics analysis is also a plus, as high-quality calls are challenges with other methods.

Daniel Kuppers Fred Hutch

There's no other technology that will allow us to screen the number of samples we need to make biological conclusions at this cost, that's why we really want to work with you

Jay Schneider TJU

We’ve always been limited by cumbersome workflows, it’s been impossible to get (EpiT) data within a week … RNA Mods are so critically important, but there’s been no technology yet that makes the analysis easy - until now

Senior Scientist $2B+ Diagnostics Company

What we offer

Turnkey Profiling

Uni-Mod, Duo-Mod, or Tri-Mod services. Send samples, receive EpiScout™ results.

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What we offer

Kits & Reagents

EpiPlex™ RNA Mod Encoding Kit and UDI Kit for in-lab workflows.

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Technology

Proximity barcoding, multi-target detection, and EpiScout™ analysis.

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RNA modifications in biology and disease

Alida Biosciences’ technologies are designed to unleash the transformative potential of epitranscriptomics in basic research and applications in RNA-centered diagnostics and therapeutics. Proximity barcoding translates sequencing-silent RNA modifications into NGS-readable barcodes.

Recent Media and Blog Posts

Beyond Transcriptomics: RNA Modifications Shape Cancer Progression

RNA modifications such as m6A, A-to-I editing, and pseudouridine influence RNA stability, translation, splicing, and immune recognition. This article explains...

Pete Dedon (MIT) and Byron Purse (AlidaBio co-founder) in conversation during an interview discussing epitranscriptomics and translational research.

Beyond the Genome – The Story of Epitranscriptomics

Share this post on LinkedIn In this insightful interview, Byron Purse (Alida Biosciences co-founder) and Pete Dedon (MIT) dive...

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AlidaBio Introduces the EpiPlex™ Duo-Mod™ Service for Concurrent m6A and Inosine Mapping with Integrated RNA Expression Profiling

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Dr. Byron Purse, professor of chemistry at San Diego State University and co-founder of AlidaBio, speaking with Dr. Don Davis during an interview for the Life Science Success podcast series.

RNA Secrets Unveiled: Byron Purse’s Biotech Breakthrough Journey

In this episode of the Life Science Success podcast, Dr. Don Davis talks with Dr. Byron Purse, professor of chemistry...

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Watch AlidaBio’s EpiPlex Platform workflow, showing step-by-step process from RNA sample to sequencing-ready library creation and analysis in the EpiScout software. Visual highlights include enrichment-based library prep using non-antibody binders, streamlined protocol steps, and data output displaying detection and quantitation of RNA modifications (m6A and inosine) alongside gene expression.

EpiPlex™ Technology in Action

Share this post on LinkedIn The EpiPlex™ Platform delivers a streamlined, end-to-end workflow for high-resolution detection and relative...

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Illustration of three ADAR enzymes as cartoon characters: ADAR1 in a lab coat labeled p110 and p150 editing RNA with Alu motifs in the background, ADAR2 as a surgeon performing precise RNA editing with a brain motif, and ADAR3 as a referee with a shield blocking RNA access, depicting adenosine-to-inosine (A-to-I) editing.

The Power of Inosine: How RNA Editing Shapes the Transcriptome

Author: Zachary Miles Senior Director of Protein Engineering Share this post on LinkedIn One of the most transformative post-transcriptional modifications...

Video explaining how AlidaBio's EpiPlex Platform for transcriptome-wide RNA modification profiling of m6A and inosine

The EpiPlex™ Platform for Multi-Target Detection of RNA Modifications

Share this post on LinkedIn Dr. Gudrun Stengel, CEO and co-founder of Alida Biosciences, introduces the role of RNA modifications...

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From RNA modification sequencing data to biological insight. A case for bioinformatics.

Author: Dana Nachmanson Sr. Bioinformatics Scientist Share this post on LinkedIn RNA-seq analysis has become a staple of modern...

No Cuts, Just Edits: Therapeutic A-to-I RNA Editing as a Safer Alternative to CRISPR’s Scalpel

Author: Gudrun Stengel CEO and Co-founder Share this post on LinkedIn CRISPR Unpacked: Promises, Successes and Roadblocks When...

What Are Those RNA Modifications Doing for Gene Regulation?

In this episode of the cc: Life Science Podcast series, Chris Conner speaks with AlidaBio CEO and co-founder Dr. Gudrun...

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